Research output per year
Research output per year
Personal profile
About
Joesph Audie, Ph.D. is Professor of Chemistry in the College of Arts & Sciences at Sacred Heart University. Dr. Audie's research interests and activities are primarily focused on: (1) developing a theoretical understanding of protein-protein and protein-peptide recognition (2) developing computational methods to predict and explain protein-protein and protein-peptide interactions and (3) applying computational methods to identify and optimize peptide-based and peptide-derived drug leads.
Additionally, Professor Audie is interested in exploring and understanding the relationship between faith and reason, especially as it pertains to the relationship between modern empirical science, Aristotelean philosophy and Thomistic theology.
Professor Audie was awarded tenure by the Board of Trustees in May 2013.
Contact Information
Chemistry Department
Science Center of Academic Bldg SC 105 F
College of Arts and Sciences
203-371-7986
Related documents
Education/Academic qualification
Ph.D. Biophysics, SUNY Stony Brook
… → 2006
M.S. Biomedical Engineering, University of Connecticut
… → 2001
B.S. Bioengineering, Hofstra University
… → 1995
External positions
CEO, NLS Life Science and Therapeutics Discovery, LLC
Feb 1 2017 → …
Cofounder, CEO and CSO, CMD Bioscience
Jan 1 2007 → Feb 1 2017
Research Interests
- Protein biophysics
Disciplines
- Analytical Chemistry
- Physical Chemistry
- Biological and Chemical Physics
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Design, Structure–Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists
Sawyer, J. R., Audie, J. A., Swanson, J., Diller, D., Santiago, S., Gribkoff, V. K., Ackerman, A., Hruby, V. J., Gobbo, G., Bellucci, M. A., Glauser, W. A., Pentelute, B. L. & Sawyer, T. K., Jan 2025, In: Molecules. 30, 1, 12.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrated Screening for Beta-Lactamases Inhibitors Identification of Pharmaceutical Hits and Lead Optimization
Sullivan, T. J., Kafel, H. W., Bedel-Franklin, K., Burt, C. A., Bayer, E. J., De Souza, L., Peredy, T., Voulo, M. A., Galasinski, Z., Fleischmann, D., Ingegneri, K., Alper, B. & Audie, J., Apr 24 2020.Research output: Contribution to conference › Poster › peer-review
Open AccessFile -
Inhibiting IL-2 Signaling and the Regulatory T-cell Pathway Using Computationally Designed Peptides
Price-Troska, T., Yang, Z.-Z., Diller, D. J., Bayden, A. S., Jarosinski, M., Audie, J. & Ansell, S. M., Feb 1 2019, In: Investigational New Drugs. 37, 1Research output: Contribution to journal › Article › peer-review
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Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides
Diller, D. J., Swanson, J., Bayden, A. S., Brown, C. J., Thean, D., Lane, D. P., Patridge, A. W., Sawyer, T. K. & Audie, J., Jan 1 2019, In: Molecules.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
An Unexpected Way Forward: Towards a More Accurate and Rigorous Protein-Protein Affinity Scoring Function by Eliminating Terms from an Already Simple Scoring Function
Swanson, J. & Audie, J., Jan 1 2018, In: Journal of Biomolecular Structure & Dynamics. 36, 1Research output: Contribution to journal › Article › peer-review